Intermediate Filament

Intermediate Filament

Intermediate filaments (IFs) are cytoskeletal components found in metazoan cells. They are composed of a family of related proteins sharing common structural and sequence features. Intermediate filaments have an average diameter of 10 nanometers, which is between that of 7 nm actin (microfilaments), and that of 25 nm microtubules, although they were initially designated 'intermediate' because their average diameter is between those of narrower microfilaments (actin) and wider myosin filaments found in muscle cells. Most types of intermediate filaments are cytoplasmic, but one type, the lamins, are nuclear.

Read more about Intermediate Filament:  Structure, Biomechanical Properties, Types, Cell Adhesion, Associated Proteins, Diseases Arising From Mutations in IF Genes

Famous quotes containing the word intermediate:

    Complete courage and absolute cowardice are extremes that very few men fall into. The vast middle space contains all the intermediate kinds and degrees of courage; and these differ as much from one another as men’s faces or their humors do.
    François, Duc De La Rochefoucauld (1613–1680)