| Gene Ontology | |
|---|---|
| Molecular function | • receptor binding • cytokine activity • interleukin-28 receptor binding |
| Cellular component | • extracellular region • extracellular space • interleukin-28 receptor complex |
| Biological process | • negative regulation of type 2 immune response • negative regulation of cell proliferation • negative regulation of interleukin-13 production • negative regulation of interleukin-5 production • positive regulation of interferon-gamma production • positive regulation of tyrosine phosphorylation of STAT protein • negative regulation of memory T cell differentiation • positive regulation of MHC class I biosynthetic process • negative regulation of T cell differentiation • negative regulation of transcription, DNA-dependent • positive regulation of transcription, DNA-dependent • positive regulation of JAK-STAT cascade • positive regulation of immune response • defense response to virus |
| Sources: Amigo / QuickGO | |
39.79 – 39.79 Mb
Interleukin-29 (IL-29) is a protein that in humans is encoded by the IL29 gene that resides on chromosome 19.
IL-29 is a member of the helical cytokine family and is a type III interferon. It is also known as IFNλ1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.