S
| Player | No.(s) | Height in Ft. | Position | Years for Rockets | School/Club Team/Country |
|---|---|---|---|---|---|
| Sampson, Ralph Ralph Sampson | 50 | 7-4 | Forward / Center | 1983-88 | Virginia |
| Scola, Luis Luis Scola | 4 | 6-9 | Forward | 2007-2012 | Argentina |
| Short, Purvis Purvis Short | 10 | 6-7 | Forward / Guard | 1987-89 | Jackson State |
| Shumate, John John Shumate | 34 | 6-9 | Forward | 1979-80 | Notre Dame |
| Siegfried, Larry Larry Siegfried | 20 | 6-3 | Guard | 1970-71 | Ohio State |
| Smith, Bobby Bobby Smith | 32 | 6-5 | Forward | 1969-70 | Tulsa |
| Smith, Greg Greg Smith | 4 | 6-5 | Forward | 1971-72 | Western Kentucky |
| Smith, Kenny Kenny Smith | 30 | 6-3 | Guard | 1990-96 | North Carolina |
| Smith, Larry Larry Smith | 13 | 6-8 | Forward / Center | 1989-92 | Alcorn State |
| Snyder, Kirk Kirk Snyder | 13 | 6-6 | Guard | 2006-08 | Nevada-Reno |
| Spanoulis, Vassilis Vassilis Spanoulis | 10 | 6-4 | Guard | 2006-07 | Greece |
| Spriggs, Larry Larry Spriggs | 35 | 6-7 | Forward | 1981 | Howard |
| Stephens, Joe Joe Stephens | 41 | 6-7 | Forward | 1997 | Arkansas-Little Rock |
| Strickland, Rod Rod Strickland | 31 | 6-3 | Guard | 2004-05 | DePaul |
| Stroud, John John Stroud | 42 | 6-7 | Forward | 1980-81 | Mississippi |
| Sura, Bob Bob Sura | 3 | 6-5 | Guard | 2004-07 | Florida State |
| Swift, Stromile Stromile Swift | 4 | 6-10 | Forward | 2005-06 | LSU |
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