Greenville is the name of several places:
- In Canada
- Laxgalts'ap, British Columbia, formerly named Greenville
- Greenville, Nova Scotia, in Yarmouth County
- Greenville Station, Nova Scotia, in Cumberland County
- Lower Greenville, Nova Scotia, in Cumberland County
- In Liberia
- Greenville, Liberia
- In the United States of America
- Greenville, Alabama
- Greenville, California, in Plumas County
- Greenville, Alameda County, California
- Greenville, Yuba County, California
- Greenville, Connecticut
- Greenville, Delaware
- Greenville, Florida
- Greenville, Georgia
- Greenville, Illinois
- Greenville, Indiana
- Greenville, Iowa
- Greenville, Kentucky
- Greenville, Louisiana
- Greenville, Maine
- Greenville, Massachusetts
- Greenville, Michigan
- Greenville, Mississippi
- Greenville, Missouri
- Greenville, Nevada
- Greenville, New Hampshire
- Greenville, Jersey City, New Jersey
- Greenville, New York (disambiguation)
- Greenville, North Carolina
- Greenville, Ohio
- Greenville, Oregon (disambiguation)
- Greenville, Pennsylvania
- Greenville Township, Somerset County, Pennsylvania
- Greenville, Rhode Island
- Greenville, South Carolina
- Greenville, Texas
- Greenville, Utah
- Greenville, Virginia
- Greenville, Wisconsin, a town
- Greenville (community), Wisconsin, an unincorporated community
- Greencastle, West Virginia, also called Greenville
- In the United Kingdom
- Greenville, County Antrim, a townland in County Antrim, Northern Ireland