Gilead's pipeline focuses on HCV, HIV, cardiovascular and respiratory disorders.
Drug Name | Description | Potential Indication | Testing Phase |
---|---|---|---|
Integrase Fixed-dose Regimen "Quad" | elvitegravir/FTC/TDF/cobicistat | HIV/AIDS | Phase III |
Truvada/TMC 278 Fixed-dose Regimen | Viread, Emtriva, and TMC 278 | HIV/AIDS | Phase III |
Elvitegravir (formerly GS-9137) | Integrase inhibitor | HIV/AIDS | Phase III |
Cobicistat (GS-9350) | Pharmacokinetic enhancer | HIV/AIDS | Phase III |
Tegobuvir (GS 9190) | Non-nucleoside polymerase inhibitor | Hepatitis C | Phase II |
Cicletanine | Antihypertensive | Pulmonary arterial hypertension | Phase II |
Aztreonam | inhalation solution | Bronchiectasis | Phase II |
Ranolazine | Late sodium current inhibitor | Coronary Artery Disease/Diabetes | Phase II |
GS 9256 | Protease inhibitor | Hepatitis C | Phase II |
GS 9310/11 | inhaled fosfomycin/tobramycin | Cystic Fibrosis/Chronic Obstructive Pulmonary Disease | Phase II |
GS 9667 (formerly CVT-3619) | Partial A1 adenosine agonist | Diabetes/Dyslipidemia | terminated |
GS 7340 | Nucleotide | HIV/AIDS | Phase I |
GS 9451 | Protease inhibitor | Hepatitis C | Phase I |
GS 5885 | NS5A inhibitor | Hepatitis C | Phase I |
GS 9620 | TLR-7 agonist | Hepatitis C/Hepatitis B | Phase I |
GS 6201 (formerly CVT-6883) | A2B adenosine antagonist | Pulmonary diseases | Phase I |
GS 6620 | Nucleotide polymerase inhibitor | Hepatitis C | Phase I |
Sofosbuvir (formerly GS 7977) | Nucleotide polymerase inhibitor | Hepatitis C | Phase III |
GS 9669 | Non-nucleotide polymerase inhibitor | Hepatitis C | pre-clinical |
GS 9411 | Epithelial sodium channel blocker | Pulmonary diseases | Phase I |
CVT-10216 | ALDH-2 inhibitor | Drug addiction | pre-clinical |
Tecadenoson | Selective A1 adenosine receptor | Atrial fibrillation | terminated |
Perfan | Enoximone | Heart failure | Phase III |
GS 9219 | Nucleotide analogue | Non-Hodgkin’s lymphoma and Chronic lymphocytic leukemia | Phase I |
GS 8374 | Protease inhibitor | HIV/AIDS | pre-clinical |
GS 424020 | Prodrug of Desisobutryl-ciclesonide and salmeterol | Asthma and Chronic obstructive pulmonary disease | pre-clinical |
GS 9148 | Nucleotide analog, phosphonomethoxy-2'-fluoro-2', 3'-dideoxydidehydroadenosine | HIV/AIDS | pre-clinical |
GS 9131 | Prodrug of GS 9148 | HIV/AIDS | pre-clinical |
GS 9224 | Integrase inhibitor | HIV/AIDS | pre-clinical |
GS 6624 | Humanized monoclonal antibody | idiopathic pulmonary fibrosis and advanced solid tumors | Phase I |
CAL-101 | PI3K Delta selective inhibitor | Chronic Lymphocytic Leukemia and Non-Hodgkin Lymphoma | Phase I |
CAL-263 | PI3K Delta selective inhibitor | inflammatory diseases | Preclinical |
CAL-120 | PI3K Delta selective inhibitor | inflammatory diseases and oncology | Preclinical |
CAL-129 | PI3K Delta selective inhibitor | inflammatory diseases and oncology | Preclinical |
CAL-253 | PI3K Delta selective inhibitor | inflammatory diseases and oncology | Preclinical |
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