Selection Effective Size
In an idealised Wright-Fisher model, the fate of an allele, beginning at an intermediate frequency, is largely determined by selection if the selection coefficient s >> 1/N, and largely determined by neutral genetic drift if s << 1/N. In real populations, the cutoff value of s may depend instead on local recombination rates. This limit to selection in a real population may be captured in a toy Wright-Fisher simulation through the appropriate choice of Ne. Populations with different selection effective population sizes are predicted to evolve profoundly different genome architectures.
Read more about this topic: Effective Population Size
Famous quotes containing the words selection, effective and/or size:
“When you consider the radiance, that it does not withhold
itself but pours its abundance without selection into every
nook and cranny”
—Archie Randolph Ammons (b. 1926)
“The message you give your children when you discipline with love is “I care too much about you to let you misbehave. I care enough about you that I’m willing to spend time and effort to help you learn what is appropriate.” All children need the security and stability of food, shelter, love, and protection, but unless they also receive effective and appropriate discipline, they won’t feel secure.”
—Stephanie Marston (20th century)
“There are obvious places in which government can narrow the chasm between haves and have-nots. One is the public schools, which have been seen as the great leveler, the authentic melting pot. That, today, is nonsense. In his scathing study of the nation’s public school system entitled “Savage Inequalities,” Jonathan Kozol made manifest the truth: that we have a system that discriminates against the poor in everything from class size to curriculum.”
—Anna Quindlen (b. 1952)