Clyne may refer to:
- Clyne (surname)
Places:
- Clyne, Neath Port Talbot, Wales
- Clyne, Highland, in Highland council area
- Clyne Castle, Swansea, Wales
- Clyne Valley Country Park, Swansea, Wales
Fictional characters in Mobile Suit Gundam Seed anime franchise:
- Lacus Clyne
- Siegel Clyne