Diseases
Some diseases result from a poorly functioning basement membrane. The cause can be genetic defects, injuries by the body's own immune system, or other mechanisms.
Genetic defects in the collagen fibers of the basement membrane cause Alport syndrome.
Non-collagenous domain basement membrane collagen type IV is autoantigen (target antigen) of autoantibodies in the autoimmune disease Goodpasture's syndrome.
A group of diseases stemming from improper function of basement membrane zone are united under the name epidermolysis bullosa.
Read more about this topic: Basement Membrane
Famous quotes containing the word diseases:
“Even diseases have lost their prestige, there aren’t so many of them left.... Think it over ... no more syphilis, no more clap, no more typhoid ... antibiotics have taken half the tragedy out of medicine.”
—Louis-Ferdinand Céline (1894–1961)
“A fiction about soft or easy deaths ... is part of the mythology of most diseases that are not considered shameful or demeaning.”
—Susan Sontag (b. 1933)
“The fantasies inspired by TB in the last century, by cancer now, are responses to a disease thought to be intractable and capricious—that is, a disease not understood—in an era in which medicine’s central premise is that all diseases can be cured.”
—Susan Sontag (b. 1933)