Americus may mean:
- Places in the United States
- Americus, Georgia, a city with a population of around 17,000
- Americus, Indiana, a small town in Washington Township
- Americus, Kansas, a city with a population of around 900
- People
- Saint Emeric of Hungary (died 1031), also known as Saint Americus or Emeric, a Hungarian prince
- Amerigo Vespucci (1454-1512) Italian merchant, explorer and cartographer whose first name was Americus in Latin
- Literature
- Americus, A graphic novel by MK Reed and Jonathon Hill