Function
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL) and physiological roles have been identified in mouse Natural Killer T cells and gamma-delta T cells. Alternate transcriptional splice variants have been characterized in human.
Read more about this topic: Zinc Finger And BTB Domain-containing Protein 16
Famous quotes containing the word function:
“No one, however powerful and successful, can function as an adult if his parents are not satisfied with him.”
—Frank Pittman (20th century)
“It is the function of vice to keep virtue within reasonable bounds.”
—Samuel Butler (1835–1902)
“Morality and its victim, the mother—what a terrible picture! Is there indeed anything more terrible, more criminal, than our glorified sacred function of motherhood?”
—Emma Goldman (1869–1940)