Zayn Al-Din Gorgani - Thesaurus of The Shah of Khwarazm

Al-Jurjani wrote the Persian medical encyclopedia, Thesaurus of the Shah of Khwarazm (also known as The Treasure of Khwarazm Shah), some time after 1110, when he moved to the northern Persian province of Khwarezm. Much of his work was dependent on Avicenna's The Canon of Medicine (c. 1025), along with al-Jurjani's own ideas not found in the Canon. The work is composed of ten volumes covering ten medical fields: anatomy, physiology, hygiene, diagnosis and prognosis, fevers, diseases particular to a part of the body, surgery, skin diseases, poisons and antidotes, and medicaments (both simple and compound). In endocrinology in particular, al-Jurjani was one of "the first to associate exophthalmos with goitre," which not repeated until Caleb Parry (1755–1822) in 1825, and later by Robert James Graves (1796–1853) and Carl von Basedow (1799–1854). Al-Jurjani also established an association between goitre and palpitation in The Treasure of Khwarazm Shah.