Yellow Fever Vaccine

Yellow fever vaccine is a vaccine used against yellow fever.

The vaccine consists of a live, but attenuated, strain of the yellow fever virus called 17D. The 17D vaccine has been used commercially since the 1950s. The mechanisms of attenuation and immunogenicity for the 17D strain are not known. However, this vaccine is very safe, with few adverse reactions having been reported and millions of doses administered, and highly effective with over 90% of vaccinees developing a measurable immune response after the first dose.

In 2013, the World Health Organization concluded, "a single dose of vaccination is sufficient to confer life-long immunity against yellow fever disease."