XR or Xr may refer to:

  • XL and XR, characters on Buzz Lightyear of Star Command
  • XR (Ford Australia), a designation given to some high-performance vehicles sold by Ford Australia
  • Cairo (graphics), the original name for a graphics library software
  • Cross-reference
  • Exchange rate
  • Extended release in certain medications, for example Adderall XR
  • Extrapolated Runs, a baseball statistic
  • Honda XR series, a line of off-road and dual-sport motorcycles manufactured by Honda
  • IOS XR, the software for Cisco Systems' high-end carrier-grade routers
  • Index register, a type of register of a CPU
  • Skywest Airlines's IATA airline code
  • labarum, the Chi-Rho monogram of Christ