Wodehouse is an English surname and may refer to:
- Sir Armine Wodehouse, 5th Baronet (c. 1714–1777), MP for Norfolk
- Armine Wodehouse (MP) (1860–1941), MP for Saffron Walden, descendant of the above
- Edmond Wodehouse (1784–1855), MP for Norfolk, and later, Norfolk East
- Edmond Robert Wodehouse (1835–1914), British Unionist politician
- Sir Edwin Frederick Wodehouse (c. 1850–1934), senior British police officer
- Sir John Wodehouse, 4th Baronet (1669–1754), British MP
- John Wodehouse, 1st Baron Wodehouse (1741–1834), British MP and then peer
- John Wodehouse, 2nd Baron Wodehouse (1770–1846), British MP and then peer
- Norman Wodehouse (1887–1941), Royal Navy vice-admiral
- P. G. Wodehouse (1881–1975), English humor writer
- Sir Philip Edmond Wodehouse (1811–1887), British colonial administrator
- Richard Wodehouse (1892–1940), cricketer
Members of the family of the Earls of Kimberley:
- John Wodehouse, 1st Earl of Kimberley (1826–1902), English statesman
- John Wodehouse, 2nd Earl of Kimberley (1848–1932), first member of the Labour Party in the House of Lords
- John Wodehouse, 3rd Earl of Kimberley (1883–1941)
- John Wodehouse, 4th Earl of Kimberley (1924–2002)
- John Wodehouse, 5th Earl of Kimberley (born 1951)
- David Wodehouse, Lord Wodehouse (born 1978), heir of the 5th Earl of Kimberley