Winterbottom's sign is seen in the early phase of African trypanosomiasis, a disease caused by the parasites Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which is more commonly known as African sleeping sickness. Dr Anthony Martinelli describes Winterbottom's sign as the swelling of lymph nodes (lymphadenopathy) along the back of the neck, in the posterior cervical chain of lymph nodes, as trypanosomes travel in the lymphatic fluid and cause inflammation.
It may be suggestive of cerebral infection.
Read more about Winterbottom's Sign: Eponym
Famous quotes containing the word sign:
“Many men are deeply moved by the mere semblance of suffering in a woman; they take the look of pain for a sign of constancy or of love.”
—Honoré De Balzac (1799–1850)