Career
After receiving a private education in a family-run school, he began apprenticing at age fourteen with his uncle, J. Morton Poole, in a machine shop near Wilmington, Delaware. After seven years, he moved to Providence, Rhode Island to run the shops of what eventually became the Corliss Steam Engine Company. Returning to West Philadelphia to start his own machine company, he eventually formed a partnership with his brother-in-law Edward Bancroft (1811–1855) in 1848. After Bancroft's death in 1855, Sellers incorporated as William Sellers & Co., which continued to operate until 1947 when it was sold to the Consolidated Machine Tool Corporation and relocated to Rochester, New York.
In 1847 Sellers was elected a member of the Franklin Institute, where he served as a member of the Board of Managers from 1857 to 1861 and again from 1864 to 1892, and as president from 1864 to 1867. At a meeting on September 15, 1864, he presented a uniform system of screw threads which with its angle and its flat top and bottom differed from Whitworth's British standard. Within a few years, the system had been adopted by the government workshops, leading railroad companies, prominent machine tool builders and others, under the various names of the United States, Sellers, or Franklin Institute Systems.
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