William Hughes

William or Bill Hughes may refer to:

• Willie Hughes (16th century), possible dedicatee of Shakespeare's Sonnets
• William Hughes, 1st Baron Dinorben (1767–1852), British industrialist, politician and benefactor
• William Hughes (writer) (1803–1861), British writer on law and angling
• William Hughes (geographer) (1818–1876), British mapmaker, professor of geography and author
• William Hughes (senator) (1872–1918), U.S. representative and senator from New Jersey
• William Alfred Carroll Hughes (1877–1940), American bishop
• William Hughes, Baron Hughes (1911–1999), Scottish Labour party politician
• William Anthony Hughes (born 1921), American Roman Catholic bishop
• William J. Hughes (born 1932), U.S. representative from New Jersey and Ambassador
• William Hughes (professor), British professor of Gothic studies, and author/editor of several books on Bram Stoker and the Gothic
• William Hughes (footballer) (1865–?), footballer who played for Liverpool F.C.
• William Hughes (As the World Turns), a fictional character on the American soap opera As the World Turns
• William Bulkeley Hughes (1797–1882), Welsh politician
• William M. Hughes, member of the Los Angeles, California, City Council
• Bill Hughes (American football) (born 1915), American football player
• Bill Hughes (first baseman) (1860–1928), baseball player
• Bill Hughes (pitcher) (1896–1963), American baseball player in 1921
• Bill Hughes (musician) (born 1930), American jazz musician
• Bill Hughes (police officer) (born 1950), Director General of Britain's Serious Organised Crime Agency
• Skinny DeVille (real name William Hughes), American rapper, member of Nappy Roots