Other Nobles
- William Douglas of Glenbervie (c. 1473–1513), killed at the Battle of Flodden
- William Douglas, Lord of Liddesdale (c. 1300–1353)
- Sir William Douglas of Nithsdale (c. 1370–c. 1392), Scottish knight
- William Douglas, Duke of Hamilton (1634–1694)
- William Douglas, 1st Duke of Queensberry (1637–1695), Scottish politician
- Sir William Douglas, 1st Baronet (died 1809), Scottish landowner and founder of Castle Douglas
- Sir William Douglas, 4th Baronet (c. 1730–1783), MP for Dumfries Burghs
- William Douglas, 4th Duke of Queensberry (1724–1810), Scottish nobleman
- William Douglas, 1st Baron Douglas of Kirtleside (1893–1969), senior commander in the Royal Air Force
- Lord William Douglas (1783–1859), British politician and landowner
- William Douglas, 1st Baron Drumlanrig (died 1427)
- William Douglas, 2nd Lord Mordington (1626–?)
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