Disruptive Technology
Full genome sequencing provides information on a genome that is orders of magnitude larger than that provided by the previous leader in genotyping technology, DNA arrays. For humans, DNA arrays currently provide genotypic information on up to one million genetic variants, while full genome sequencing will provide information on all six billion bases in the human genome, or 3,000 times more data. Because of this, full genome sequencing is considered disruptive to the DNA array markets as the accuracy of both range from 99.98% to 99.999% (in non-repetitive DNA regions) and their consumables cost of $5000 per 6 billion base pairs is competitive (for some applications) with DNA arrays ($500 per 1 million basepairs). Agilent, another established DNA array manufacturer, is working on targeted (selective region) genome sequencing technologies. It is thought that Affymetrix, the pioneer of array technology in the 1990s, has fallen behind due to significant corporate and stock turbulence and is currently not working on any known full genome sequencing approach. It is unknown what will happen to the DNA array market once full genome sequencing becomes commercially widespread, especially as companies and laboratories providing this disruptive technology start to realize economies of scale. It is postulated, however, that this new technology may significantly diminish the total market size for arrays and any other sequencing technology once it becomes commonplace for individuals and newborns to have their full genomes sequenced.
Read more about this topic: Whole Genome Sequencing
Famous quotes containing the word technology:
“Radio put technology into storytelling and made it sick. TV killed it. Then you were locked into somebody else’s sighting of that story. You no longer had the benefit of making that picture for yourself, using your imagination. Storytelling brings back that humanness that we have lost with TV. You talk to children and they don’t hear you. They are television addicts. Mamas bring them home from the hospital and drag them up in front of the set and the great stare-out begins.”
—Jackie Torrence (b. 1944)