Whedon may refer to:
- Joss Whedon, a writer, director, and executive producer for television
- Tom Whedon, a writer for television, Joss Whedon's father
- John Whedon, a writer for television, Tom Whedon's father and Joss Whedon's grandfather
- Zack Whedon, a writer for television, son of Tom Whedon and brother of Joss Whedon
- Jed Whedon, a screenwriter and musician, son of Tom Whedon and brother of Joss Whedon
Fictional characters:
- Evangeline Whedon, a fictional character in the Marvel Comics Universe
- Joe Whedon, a fictional character on the primetime show Brothers & Sisters
- Sarah Whedon, a fictional character on the primetime show Brothers & Sisters