What's up may refer to:
- What's Up? (musical), a Lerner and Loewe musical
- "What's Up?" (song), a song by 4 Non Blondes
- What's Up!, a Swedish boyband
Famous quotes containing the word what:
“Method goes far to prevent trouble in business: for it makes the task easy, hinders confusion, saves abundance of time, and instructs those that have business depending, both what to do and what to hope.”
—William Penn (1644–1718)