Vojo Deretic - Publications

Publications

• Gutierrez, M. G., S. S. Master, S. B. Singh, G. A. Taylor, M. I. Colombo, and V. Deretic. 2004. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119:1-20.

• Singh, S.B., A. Davis, G. A. Taylor, and V. Deretic. 2006. Human IRGM Induces Autophagy to Eliminate Intracellular Mycobacteria. Science 3 August 2006: 11295771 doi:10.1126/science.1129577

Harris, J., S. A. De Haro, S. S. Master, J. Keane, E., A. Roberts, M. Delgado, and V. Deretic. 2007. T helper 2 cytokines inhibit autophagic control of intracellular M. tuberculosis. Immunity, 27:505-517.

Levine B and Deretic. 2007. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol. 7:767-77.

Deretic, V., and D. J. Klionsky. 2008. How cells clean house. Scientific American 298:74-81.

Delgado-Vargas, M.A., Elmaoued, R.A., David, A.S., Kyei, G., and Deretic, V. 2008. Toll-like receptors control autophagy. EMBO J., 27(7): 1110-21.

Kyei, G.B., Dinkins, C., Davis, A.S., Roberts, E., Singh, S.B., Dong, C., Wu, L., Kominami, E., Ueno, T., Yamamoto, A., Federico, M., Panganiban, A., Vergne, I., and Deretic., V. 2009. Autophagy pathway intersects with HIV-1 biogenesis and regulates viral yields in macrophages. J Cell Biol 186:255-68.

Deretic, V., and Levine, B. (2009). Autophagy, Immunity, and Microbial Adaptations. Cell Host and Microbe 5:527-549.

Vergne, I., E. Roberts, R.E. Elmaoued, V. Tosch, M. A Delgado, T. Proikas-Cezanne, J. Laporte and V. Deretic. (2009) Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy. EMBO J. 28:2244-2258.

Deretic, V. 2010. Autophagy in infection. Current opinion in cell biology 22:252-262.

Ponpuak, M., Davis, A.S., Roberts, E.A., Delgado, M.A., Dinkins, C., Zhao, Z., Virgin, H.W.t., Kyei, G.B., Johansen, T., Vergne, I., and Deretic, V. 2010. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity 32:329-341.

Singh, S. B., W. Ornatowski, I. Vergne, J. Naylor, M. Delgado, E. Roberts, M. Ponpuak, S. Master, M. Pilli, E. White, M. Komatsu, and V. Deretic. 2010. Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria. Nat Cell Biol 12:1154-1165.

Dupont, N., Jiang, S., Pilli, M., Ornatowski, W., Bhattacharya, D., and Deretic, V. 2011. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. Embo J 30:4701-4711.

Deretic, V. 2012. Autophagy: an emerging immunological paradigm. J Immunol 189:15-20.

Deretic, V., S. Jiang, and N. Dupont. 2012. Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation. Trends Cell Biol 22:397-406.

Deretic, V. 2012. Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors. Curr Opin Immunol 24:21-31.

Pilli, M., J. Arko-Mensah, M. Ponpuak, E. Roberts, S. Master, M. A. Mandell, N. Dupont, W. Ornatowski, S. Jiang, S. B. Bradfute, J. A. Bruun, T. E. Hansen, T. Johansen, and V. Deretic. 2012. TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation. Immunity 37:223-234.