Treatment
Vibrio vulnificus wound infections have a mortality of approximately 25%. In patients in whom the infection worsens into septicemia, typically following ingestion, the mortality rate rises dramatically to 50%. The majority of these patients die within the first 48 hours of infection. The optimal treatment is not known, but, in one retrospective study of 93 patients in Taiwan, use of a third-generation cephalosporin and a tetracycline (e.g., ceftriaxone and doxycycline, respectively) were associated with an improved outcome. Prospective clinical trials are needed to confirm this finding, but in vitro data support the supposition this combination is synergistic against Vibrio vulnificus. Similarly, the American Medical Association and the Centers for Disease Control and Prevention recommend treating the patient with a quinolone or intravenous doxycycline with ceftazidime.
V. vulnificus often causes large, disfiguring ulcers that require extensive debridement or even amputation.
V. vulnificus is commonly found in the Pacific Northwest.
Read more about this topic: Vibrio Vulnificus
Famous quotes containing the word treatment:
“Ambivalence reaches the level of schizophrenia in our treatment of violence among the young. Parents do not encourage violence, but neither do they take up arms against the industries which encourage it. Parents hide their eyes from the books and comics, slasher films, videos and lyrics which form the texture of an adolescent culture. While all successful societies have inhibited instinct, ours encourages it. Or at least we profess ourselves powerless to interfere with it.”
—C. John Sommerville (20th century)
“The motion picture made in Hollywood, if it is to create art at all, must do so within such strangling limitations of subject and treatment that it is a blind wonder it ever achieves any distinction beyond the purely mechanical slickness of a glass and chromium bathroom.”
—Raymond Chandler (1888–1959)
“Judge Ginsburg’s selection should be a model—chosen on merit and not ideology, despite some naysaying, with little advance publicity. Her treatment could begin to overturn a terrible precedent: that is, that the most terrifying sentence among the accomplished in America has become, “Honey—the White House is on the phone.””
—Anna Quindlen (b. 1952)