Carcinogenic Effects
It is a source of jervine and cyclopamine, teratogens which can cause prolonged gestation associated with birth defects such as holoprosencephaly and cyclopia in animals such as sheep, horses, and other mammals that graze upon it. These substances inhibit the hedgehog signaling pathway.
Read more about this topic: Veratrum Californicum
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—Ralph Waldo Emerson (18031882)