Carcinogenic Effects
It is a source of jervine and cyclopamine, teratogens which can cause prolonged gestation associated with birth defects such as holoprosencephaly and cyclopia in animals such as sheep, horses, and other mammals that graze upon it. These substances inhibit the hedgehog signaling pathway.
Read more about this topic: Veratrum Californicum
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“Virtues are not emotions. Emotions are movements of appetite, virtues dispositions of appetite towards movement. Moreover emotions can be good or bad, reasonable or unreasonable; whereas virtues dispose us only to good. Emotions arise in the appetite and are brought into conformity with reason; virtues are effects of reason achieving themselves in reasonable movements of the appetites. Balanced emotions are virtues effect, not its substance.”
—Thomas Aquinas (c. 12251274)