VACTERL association (also VATER syndrome) is a non-random association of birth defects. The reason it is called an association, rather than a syndrome is that while the complications are not pathogenetically related they tend to occur together more frequently than expected by chance. In general, the etiology of "associations" are not defined.
Each child with this condition can be unique. At present this condition is treated after birth with issues being approached one at a time. Causes of this association are debated. VACTERL association can be linked to other similar conditions such as Klippel Feil and Goldenhar Syndrome including crossovers of conditions.
No specific genetic or chromosome problem has been identified with VACTERL association. VACTERL can be seen with some chromosomal defects such as Trisomy 18 and is more frequently seen in babies of diabetic mothers. VACTERL association, however, is most likely caused by multiple factors.
VACTERL association specifically refers to the abnormalities in structures derived from the embryonic mesoderm.
Read more about VACTERL Association: Features, Epidemiology, Pathology
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“The aim of every political association is the preservation of the natural and imprescriptible rights of man. These rights are liberty, property, security and resistance to oppression.”
—French National Assembly. Declaration of the Rights of Man (drafted and discussed August 1789, published September 1791)