Top Cited Publications
- Cummings, S. R.; Eckert, S.; Krueger, K. A.; Grady, D.; Powles, T. J.; Cauley, J. A.; Norton, L.; Nickelsen, T. et al. (1999). "The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation". JAMA: the Journal of the American Medical Association 281 (23): 2189–2197. doi:10.1001/jama.281.23.2189. PMID 10376571. edit (1,140 citations as of July 3, 2012).
- Furr, B. J.; Jordan, V. C. (1984). "The pharmacology and clinical uses of tamoxifen". Pharmacology & therapeutics 25 (2): 127–205. doi:10.1016/0163-7258(84)90043-3. PMID 6438654. edit (751 citations as of July 3, 2012).
- Love, R. R.; Mazess, R. B.; Barden, H. S.; Epstein, S.; Newcomb, P. A.; Jordan, V. C.; Carbone, P. P.; Demets, D. L. (1992). "Effects of Tamoxifen on Bone Mineral Density in Postmenopausal Women with Breast Cancer". New England Journal of Medicine 326 (13): 852–856. doi:10.1056/NEJM199203263261302. PMID 1542321. edit (723 citations as of July 3, 2012).
- Vogel, V.G., Costantino, J.P., Wickerham, D.L., Cronin, W.M., Cecchini, R.S., Atkins, J.N., Bevers, T.B., Fehrenbacher, L., Pajon (jr), E.R., Wade, J.L. III, Robidoux, A., Margolese, R.G., James, J., Lippman, S.M., Runowicz, C.D., Ganz, P.A., Reis, S.E., McCaskill-Stevens, W., Ford, L.G., Jordan, V.C. and Wolmark, N. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. Journal of the American Medical Association 295:2727-41, 2006. (588 citations as of July 3, 2012).
- MacGregor, J. I.; Jordan, V. C. (1998). "Basic guide to the mechanisms of antiestrogen action". Pharmacological reviews 50 (2): 151–196. PMID 9647865. edit (467 citations as of July 3, 2012).
- Jordan, V. C. (1984). "Biochemical pharmacology of antiestrogen action". Pharmacological reviews 36 (4): 245–276. PMID 6395141. edit (425 citations as of July 3, 2012).
- Jordan, V.C., Collins, M.M., Rowsby L. and Prestwich, G. A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity. Journal of Endocrinology 75:305-316, 1977. (400 citations as of July 3, 2012).
- Jordan, V.C. and Murphy, C. S. Endocrine pharmacology of antiestrogens as antitumor agents. Endocrine Reviews 11:578-610, 1990. (382 citations as of July 3, 2012).
- Cauley, J. A., Norton, L., Lippman, M. E., Eckert, S., Krueger, K. A., Purdie, D. W., Farrerons, J., Karasik, A., Mellstrom, D., Ng, K. W., Stepan, J. J., Powles, T. J., Morrow, M., Costa, A., Silfen, S. L., Walls, E. L., Schmitt, H., Muchmore, D. B. and Jordan, V. C. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Breast Cancer Research and Treatment 65: 125-134, 2001. (349 citations as of July 3, 2012).
- Lerner, L.J. and Jordan, V.C. Development of antiestrogens and their use in breast cancer (Eighth Cain Memorial award lecture). Cancer Research 50:4177-4189, 1990. (341 citations as of July 3, 2012).
- Gottardis, M.M., Robinson, S. P., Satyaswaroop, P.G. and Jordan, V.C. Contrasting actions of tamoxifen on endometrial and breast tumor growth in the athymic mouse. Cancer Research 48:812-815, 1988. (339 citations as of July 3, 2012).
- Gottardis, M.M. and Jordan, V.C. Development of tamoxifen-stimulated growth of MCF 7 tumors in athymic mice after long-term antiestrogen administration. Cancer Research 48:5183-5187, 1988. (332 citations as of July 3, 2012).
- Jordan, V.C. Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata. European Journal of Cancer 12:419-424, 1976. (304 citations as of July 3, 2012).
- Love, R.R., Wiebe, D. A., Newcomb, P.A., Cameron, L., Leventhal, H., Jordan, V.C., Feyzi, J. and DeMets, D. L. Effects of tamoxifen on cardiovascular risk factors in postmenopausal women. Annals of Internal Medicine 115:860-864, 1991. (298 citations as of July 3, 2012).
- Gottardis, M. M. and Jordan, V.C. The antitumor actions of keoxifene (raloxifene) and tamoxifen in the N nitrosomethylurea-induced rat mammary carcinoma model. Cancer Research 47:4020-4024, 1987. (261 citations as of July 3, 2012).
- Love, R.R., Newcomb, P.A., Wiebe, D. A., Surawicz, T.S., Jordan, V.C., Carbone, P.P. and DeMets, D.L. Effects of tamoxifen therapy on lipid and lipoprotein levels in postmenopausal patients with node-negative breast cancer. Journal of National Cancer Institute 82:1327 1331, 1990. (250 citations as of July 3, 2012).
- Jordan, V.C., Phelps, E. and Lindgren J.U. Effects of antiestrogens on bone in castrated and intact female rats. Breast Cancer Research and Treatment 10:31-35, 1987. (230 citations as of July 3, 2012).
- Jiang, S.Y. and Jordan, V.C. Growth regulation of estrogen receptor negative breast cancer cells transfected with cDNA's for estrogen receptor. Journal of the National Cancer Institute 84:580-591, 1992. (218 citations as of July 3, 2012).
- Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part I: Receptor interactions. Journal of Medicinal Chemistry 46:883-908, 2003.(210 citations as of July 3, 2012).
- Jordan, V.C. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. Part II: Clinical considerations and new agents. Journal of Medicinal Chemistry 46:1081-1111, 2003.(200 citations as of July 3, 2012).
- Gottardis, M.M., Jiang, S.Y., Jeng, M.H. and Jordan, V.C. Inhibition of tamoxifen-stimulated growth of an MCF-7 tumor variant in athymic mice by novel steroidal antiestrogens. Cancer Research 49:4090-4093, 1989. (198 citations as of July 3, 2012).
- Pink, J.J. and Jordan, V.C. Models of estrogen receptor regulation by estrogens and antiestrogens in breast cancer cell lines. Cancer Research 56:2321-2330, 1996. (192 citations as of July 3, 2012).
- Trump, D.L., Smith, D.C., Ellis, P.G., Rogers, M.P., Schold, S.C., Winer, E.P., Ponella, T.J., Jordan, V.C. and Fine, R.L. High dose oral tamoxifen, a potential multidrug resistance reversal agent: Phase I trial in combination with vinblastine. Journal of the National Cancer Institute 84:1811-1816, 1992. (189 citations as of July 3, 2012).
- Jordan, V.C. A current view of tamoxifen for the treatment and prevention of breast cancer (Gaddum Memorial Lecture). British Journal of Pharmacology 110:507-517, 1993. (187 citations as of July 3, 2012).
- Jordan, V.C. and Morrow, M.M. Tamoxifen, raloxifene and the prevention of breast cancer. Endocrine Reviews 20:253-278, 1999. (176 citations as of July 3, 2012).
- Jordan, V.C. Tamoxifen: a most unlikely pioneering medicine. Nature Reviews Drug Discovery 2:205-213, 2003. (173 citations as of July 3, 2012).
- Jordan, V.C. and Allen, K.E. Evaluation of the antitumour activity of the nonsteroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model. European Journal of Cancer 16:239-251, 1980. (170 citations as of July 3, 2012).
- Jensen, E.V. and Jordan, V.C. The estrogen receptor: a model for molecular medicine. Clinical Cancer Research 9:1980-1989, 2003. (161 citations as of July 3, 2012).
- Robinson, S.P., Langan-Fahey, S.M., Johnson, D.A. and Jordan, V.C. Metabolites, pharmacodynamics and pharmacokinetics of tamoxifen in rats and mice compared to the breast cancer patient. Drug Metabolism and Disposition 19:36-43, 1991. (152 citations as of July 3, 2012).
- Jordan, V.C. Selective estrogen receptor modulation: concept and consequences in cancer. Cancer Cell 5:207-213, 2004. (146 citations as of July 3, 2012).
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