UTY (gene)

UTY (gene)

Identifiers Symbols UTY; UTY1 External IDs OMIM: 400009 HomoloGene: 56022 GeneCards: UTY Gene

Gene Ontology
Molecular function	• oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen • metal ion binding • histone demethylase activity (H3-K36 specific)
Cellular component	• nucleus
Biological process	• in utero embryonic development • heart development • regulation of chromatin silencing • establishment of protein localization • cardiac muscle cell contraction
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7404 n/a Ensembl ENSG00000183878 n/a UniProt O14607 n/a RefSeq (mRNA) NM_001258249 n/a RefSeq (protein) NP_001245178 n/a Location (UCSC) Chr Y:
15.36 – 15.59 Mb n/a PubMed search n/a

Histone demethylase UTY is an enzyme that in humans is encoded by the UTY gene.

This gene encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts. Alternative splicing results in multiple transcript variants encoding different isoforms.