Major Intersections
- U.S. Route 425 in Clayton, Louisiana
- Interstate 20 and U.S. Route 80 in Tallulah, Louisiana
- U.S. Route 82 concurrent between Fairview, Arkansas and Lake Village, Arkansas
- U.S. Route 165 concurrent between Masonville, Arkansas and Dumas, Arkansas
- U.S. Route 425 east of Pine Bluff, Arkansas
- U.S. Route 79 in Pine Bluff
- U.S. Route 270 in White Hall, Arkansas
- U.S. Route 167 south of Little Rock, Arkansas
- Interstate 30 in Little Rock
- Interstate 40 concurrent between North Little Rock and Conway, Arkansas
- U.S. Route 412 in Bellefonte, Arkansas
- U.S. Route 62 concurrent between Bellefonte and Bear Creek Springs, Arkansas
- U.S. Route 60 and Interstate 44 near Springfield, Missouri
- U.S. Route 54 near Preston, Missouri
- U.S. Route 50 in Sedalia, Missouri
- Interstate 70 / U.S. Route 40 south of Marshall, Missouri
- U.S. Route 24 concurrent between Waverly, Missouri and Carrollton, Missouri
- U.S. Route 36 near Chillicothe, Missouri
- U.S. Route 136 in Princeton, Missouri
- U.S. Route 34 near Lucas, Iowa
- U.S. Route 69 concurrent between south of Indianola, Iowa and Des Moines, Iowa
- Interstate 235 in Des Moines
- Interstate 80 east of Des Moines
- U.S. Route 30 near Colo, Iowa
- U.S. Route 20 concurrent near Iowa Falls, Iowa
- U.S. Route 18 in Mason City, Iowa
- Interstate 35 near Albert Lea, Minnesota
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