Major Junctions
| County | Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|---|
| Fulton |
Bethel Township | 0.0 | 0.0 | I-70 east / US 522 south (Eisenhower Memorial Highway) – Hancock, Berkeley Springs, WV, Winchester, VA | Maryland state line |
| 2.6 | 4.2 | I-70 west to PA 484 – Breezewood | Exit 168 (I-70); north end of concurrency with I-70 | ||
| 6.6 | 10.6 | PA 643 west (Flickerville Road) | Eastern terminus of PA 643 | ||
| Belfast Township | 10.2 | 16.4 | PA 655 south (Thompson Road) | South end of concurrency with PA 655 | |
| 11.1 | 17.9 | PA 655 north (Pleasant Ridge Road) | North end of concurrency with PA 655 | ||
| Ayr Township | 17.1 | 27.5 | PA 928 south (Big Cove Tannery Road) | Northern terminus of PA 928 | |
| McConnellsburg | 23.6 | 38.0 | PA 16 east (Lincoln Way) / Lincoln Way west – Cove Gap, Mercersburg | Western terminus of PA 16 | |
| Todd Township | 24.5 | 39.4 | US 30 (Lincoln Highway) – Breezewood, Chambersburg | Interchange | |
| Dublin Township | 31.2 | 50.2 | PA 475 west (Waterfall Road) – Hustontown | Eastern terminus of PA 475 | |
| 32.4 | 52.1 | I-76 / Penna. Tpk. – Harrisburg, Pittsburgh | Exit 180 / Fort Littleton interchange (I-76 / PA Turnpike) | ||
| Huntingdon |
Dublin Township | 45.2 | 72.7 | PA 35 north – Mifflin | Southern terminus of PA 35 |
| 45.3 | 72.9 | PA 641 east – Roxbury | Western terminus of PA 641 | ||
| Orbisonia | 50.9 | 81.9 | PA 994 west (Elliot Street) / Elliot Street east – Rockhill | Eastern terminus of PA 994 | |
| Shirley Township | 60.3 | 97.0 | PA 103 north | Southern terminus of PA 103 | |
| Mifflin |
Wayne Township | 62.0 | 99.8 | US 22 west (William Penn Highway) – Huntingdon, Altoona | South end of concurrency with US 22 |
| Granville Township | 80.6 | 129.7 | US 22 Bus. east – Lewistown |
Western terminus of US 22 Bus. | |
| Derry Township | 84.7 | 136.3 | US 322 west / Electric Avenue – State College | Directional interchange with US 322; partial cloverleaf with Electric Avenue; south end of concurrency with US 322 | |
| Lewistown | 85.4 | 137.4 | US 22 / US 322 east / Walnut Street west – Harrisburg | Partial cloverleaf interchange; US 522 exits onto Walnut Street east via Logan Street; north end of concurrency with US 22 and US 322 | |
| Snyder |
Spring Township | 106.4 | 171.2 | PA 235 south – McAlisterville | South end of concurrency with PA 235 |
| 107.3 | 172.7 | PA 235 north – Troxelville | North end of concurrency with PA 235 | ||
| Middleburg | 116.6 | 187.6 | PA 104 north (Main Street) / Market Street east – Mifflinburg | South end of concurrency with PA 104 | |
| 116.9 | 188.1 | PA 104 south (Wausau Road) – Liverpool | North end of concurrency with PA 104 | ||
| Selinsgrove | 126.5 | 203.6 | PA 204 north / Broad Street – New Berlin | Southern terminus of PA 204 | |
| Monroe Township | 127.5 | 205.2 | US 11 (Susquehanna Trail) / US 15 – Harrisburg, Williamsport, Scranton | Partial cloverleaf interchange | |
Read more about this topic: U.S. Route 522 In Pennsylvania Famous quotes containing the word major:“With Major Lawrence, mercy is a passion. With me, it is merely good manners. You may judge which motive is the more reliable.” | |||||