Major Intersections
| County | Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|---|
| Hamilton |
Elizabethtown | 0.00 | 0.00 | US 50 west | Indiana state line |
| Cleves | 3.73 | 6.00 | SR 128 north | Southern terminus of SR 128 | |
| 4.49 | 7.23 | SR 264 east | Western terminus of SR 264 | ||
| Cincinnati | 18.60 | 29.93 | SR 264 west | Western end of concurrency with SR 264 | |
| 18.74 | 30.16 | Warsaw Avenue/Elberon Avenue | Westbound exit and eastbound entrance only | ||
| 19.31 | 31.08 | West Mehring Way | Eastbound exit only | ||
| 19.54 | 31.45 | Harriet Street | Westbound entrance only | ||
| 19.76 | 31.80 | Freeman Avenue | Full eastbound access; westbound entrance only | ||
| 19.80 | 31.87 | Linn Street | Eastbound entrance only; westbound exit | ||
| 20.13 | 32.40 | Gest Street | Westbound exit only | ||
| 20.22 | 32.54 | US 27 / US 42 / US 52 / US 127 SR 264 east |
Eastern end of concurrency with SR 264 Exit to US 27/42/52/127 |
||
| 20.28 | 32.64 | I-71 south / I-75 | Western end of I–71 concurrency | ||
| 21.37 | 34.39 | I-71 north – Columbus | Eastern end of concurrency with I-71, I-71 exit 1J | ||
| 21.91 | 35.26 | I-471 south–Newport | Access to I-471 Southbound only, I-471 exit 6A | ||
| 22.42 | 36.08 | Martin Drive | Eastbound exit and westbound entrance | ||
US 50 Truck / US 52 |
Eastbound exit; all trucks must exit | ||||
| 27.64 | 44.48 | SR 32 east / SR 125 east / SR 561 north | Western terminus of SR 32 and SR 125 Southern terminus of SR 561 |
||
| 28.25 | 45.46 | US 50 Truck west (Eastern Avenue) |
Eastbound entrance and westbound exit | ||
| Terrace Park | 36.04 | 58.00 | SR 28 begins / SR 126 west | Eastern terminus of SR 126 | |
| Clermont |
Milford | 36.91 | 59.40 | SR 28 east | Western end of SR 28 concurrency |
| 37.55 | 60.43 | SR 131 east | Western terminus of SR 131 | ||
| 39.11– 39.26 |
62.94– 63.18 |
SR 450 west to I-275 | Eastern terminus of SR 450; access to I–275 | ||
| Stonelick | 43.62 | 70.20 | SR 222 south | Northern terminus of SR 222 | |
| Owensville | 46.83 | 75.37 | SR 132 | Western end of concurrency with SR 132 | |
| 47.19 | 75.94 | SR 132 / SR 276 | Eastern end of concurrency with SR 132; northern terminus of SR 276 | ||
| Monterey | 50.88 | 81.88 | SR 133 | ||
| Marathon | 54.26 | 87.32 | SR 286 east | Western terminus of SR 286 | |
| Brown |
Vera Cruz | 57.35 | 92.30 | SR 131 | |
| Fayetteville | 59.30 | 95.43 | US 68 | ||
| St. Martin | 61.25 | 98.57 | SR 251 north | Southern terminus of SR 251 | |
| Highland |
Dodsonville | 65.68 | 105.70 | SR 134 south | Western end of concurrency with SR 134 |
| 65.77 | 105.85 | SR 134 north | Eastern end of concurrency with SR 134 | ||
| Allenburg | 67.76 | 109.05 | SR 135 north | Southern terminus of SR 135 | |
| Hillsboro | 76.28 | 122.76 | SR 124 west | Western end of concurrency with SR 124 | |
| 76.57 | 123.23 | SR 73 north | Western end of SR 73 concurrency | ||
| 76.75 | 123.52 | US 62 / SR 73 south / SR 138 | Eastern end of SR 73 concurrency | ||
| 77.18 | 124.21 | SR 124 east | |||
| Rainsboro | 86.29 | 138.87 | SR 753 south | Western end of concurrency with SR 753 | |
| 87.23 | 140.38 | SR 753 north | Eastern end of concurrency with SR 753 | ||
| Ross |
Bainbridge | 94.85 | 152.65 | SR 41 south | Western end of concurrency with SR 41 |
| 95.75 | 154.09 | SR 41 north | Eastern end of concurrency with SR 41 | ||
| Slate Mills | 110.17 | 177.30 | SR 28 west | Eastern terminus of SR 28 | |
| Chillicothe | 114.84 | 184.82 | SR 104 north | Western end of concurrency with SR 104 | |
| 115.18 | 185.36 | SR 772 south | Northern terminus of SR 772 | ||
| 115.60 | 186.04 | US 23 Bus. north / SR 159 north |
Southern end of concurrency with US 23 Business; southern terminus of SR 159 | ||
| 116.12 | 186.88 | US 23 Bus. south / SR 104 south |
Soythern end of Business US 23 concurrency; Eastern end of SR 104 concurrency | ||
| 118.14 | 190.13 | US 23 north / US 35 | Interchange; access to westbound US 35 | ||
| 118.61 | 190.88 | US 35 | Northern end of US 35 concurrency; eastbound entrance and westbound exit | ||
| Schrader | 120.13 | 193.33 | US 35 east – Jackson | Southern end of US 35 concurrency | |
| Londonderry | 127.07 | 204.50 | SR 327 north | Western end of concurrency with SR 327 | |
| Vinton |
SR 327 south | Eastern end of concurrency with SR 327 | |||
| Ratcliffburg | SR 671 west | Eastern terminus of SR 671 | |||
| Allensville | SR 683 south | Northern terminus of SR 683 | |||
| McArthur | SR 93 | ||||
| SR 677 north | Southern terminus of SR 677 | ||||
| Prattsville | SR 278 north | Southern terminus of SR 278 | |||
| Bolins Mills | SR 356 north | Southern terminus of SR 356 | |||
| Athens |
Albany | SR 143 south | Northern terminus of SR 143 | ||
| SR 32 west | Western end of concurrency with SR 32 | ||||
| SR 681 | |||||
| Athens | US 33 east – Pomeroy, Ravenswood | Western end of concurrency with US 33; Exit 18 | |||
| SR 682 north | Southern terminus of OH-681; Exit 17 | ||||
| US 33 west – Columbus | Eastern end of concurrency with US 33; Exit 16 | ||||
| Canaanville | SR 690 north | Southern terminus of SR 690 | |||
| Guysville | SR 329 north | Southern terminus of SR 329 | |||
| Coolville | SR 7 south – Pomeroy, Gallipolis | Western end of concurrency with SR 7 Interchange |
|||
| SR 144 | |||||
| Washington |
Little Hocking | SR 124 west | Eastern terminus of SR 124 | ||
| Redbush | SR 555 north | Southern terminus of SR 555 | |||
| Porterfield | SR 618 east | Western terminus of SR 618 | |||
| SR 339 | Interchange | ||||
| SR 7 north / SR 32 east | Eastern end of concurrencies with SR 7 and SR 32 Interchange |
||||
| SR 618 | |||||
| Ohio River |
Blennerhassett Island Bridge (state line) | ||||
| Wood |
Parkersburg | US 50 east | |||
|
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Read more about this topic: U.S. Route 50 In Ohio
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