Major Intersections
| County | Location | Mile | km | Exit | Destinations | Notes |
|---|---|---|---|---|---|---|
| Washington |
Donegal Township | 0.0 | 0.0 | US 40 (National Road) | US 40 enters Pennsylvania from West Virginia. | |
| Claysville | 6.3 | 10.1 | PA 231 (Bell Avenue) | Western terminus of concurrency. | ||
| 6.5 | 10.5 | PA 231 north (Wayne Street) | Eastern terminus of concurrency. | |||
| Buffalo Township | 10.3 | 16.6 | PA 221 (Green Valley Road/Bridge Road) | |||
| North Franklin Township | 14.7 | 23.7 | I-70 | Interchange, I-79 exit 15. | ||
| Washington | 16.2 | 26.1 | PA 18 north (Jefferson Avenue) | Western terminus of concurrency. | ||
| 16.4 | 26.4 | PA 136 (Beau Street) | Western terminus of PA 136. | |||
| 16.8 | 27.0 | PA 18 south (Main Street) | Eastern terminus of concurrency. | |||
| 16.9 | 27.2 | US 19 north (College Street) | Western terminus of concurrency. | |||
| Laboratory | 18.9 | 30.4 | US 19 south (Waynesburg Road) | Eastern terminus of concurrency. | ||
| Amwell Township | 19.4 | 31.2 | I-79 | Interchange, I-79 exit 33. | ||
| Glyde | 23.5 | 37.8 | PA 519 | Southern terminus of PA 519. | ||
| North Bethlehem Township | 27.3 | 43.9 | PA 917 | Southern terminus of PA 917. | ||
| Centerville | 34.9 | 56.2 | PA 481 (Old National Pike) | Southern terminus of PA 481. | ||
| West Brownsville | West end of freeway | |||||
| 37.7 | 60.7 | A | Toll PA 43 / PA 88 south – Fredericktown | PA 43 exit 30. Western terminus of concurrency with PA 88. |
||
| 37.7 | 60.7 | B | Toll PA 43 north – California | PA 43 exit 30. | ||
| 39.3 | 63.2 | PA 88 north (Blaine Avenue) – California, West Brownsville | Eastern terminus of concurrency with PA 88. | |||
| Fayette |
Brownsville | Brownsville | ||||
| East end of freeway | ||||||
| Brownsville Township | PA 166 (Thornton Road) | Northern terminus of PA 166. | ||||
| Redstone Township | Toll PA 43 | Interchange, Alternative route to Uniontown. | ||||
| Uniontown | West end of freeway | |||||
| 51.3 | 82.6 | US 119 north / US 40 Bus. (Main Street) – Connellsville |
Western terminus of concurrency with US 119, western terminus of US 40 BUS. |
|||
| South Union Township | 52.0 | 83.7 | PA 21 (McClellandtown Road) | |||
| Walnut Hill Road | ||||||
| 54.2 | 87.2 | US 119 / PA 43 south – Morgantown | No westbound exit, eastern terminus of concurrency. | |||
| To US 119 / PA 43 south (Morgantown Road) | Westbound exit | |||||
| Hopwood | 56.9 | 91.6 | US 40 Bus. (National Pike) – Uniontown |
Eastern terminus of US 40 BUS. | ||
| East end of freeway | ||||||
| Farmington | 65.7 | 105.7 | PA 381 south | Western terminus of concurrency. | ||
| 65.8 | 105.9 | PA 381 north | Eastern terminus of concurrency. | |||
| Henry Clay Township | 73.3 | 118.0 | PA 281 south | Western terminus of concurrency. | ||
| 73.5 | 118.3 | PA 281 north | Eastern terminus of concurrency. | |||
| Somerset |
Addison | 80.5 | 129.6 | PA 523 | Southern terminus of PA 523. | |
| Addison Township | 82.3 | 132.4 | US 40 (National Pike) | US 40 leaves Pennsylvania and enters Maryland. | ||
Read more about this topic: U.S. Route 40 In Pennsylvania Famous quotes containing the word major:“That is my major preoccupation—memory, the kingdom of memory. I want to protect and enrich that kingdom, glorify that kingdom and serve it.” | ||||||