Urea Reduction Ratio - History and Overview

History and Overview

The URR was first popularized by Lowrie and Lew in 1991 as a method of measuring amount of dialysis that correlated with patient outcome. This method is very useful because of its simplicity. It permits easy monitoring of the amount of dialysis therapy delivered to individual patients, as well as across dialysis units, groups of units, states, regions, or countries, because monthly predialysis and postdialysis urea nitrogen values are routinely measured. It also permits quality control and improvement initiatives and regulatory oversight. The United States Renal Data Systems (USRDS) publishes annual data regarding the URR values being delivered to dialysis patients across the United States. The ESRD networks monitor therapy across groups of states. The European Renal Association (ERA-EDTA) Registry covers most European countries, and DOPPS (Dialysis Outcomes Practice Patterns Study) records and analyzes URR and other data from selected dialysis units located in countries across the world.

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