Films
- The Jungle (1906) was adapted for film in 1914, with George Nash playing Jurgis Rudkus and Gail Kane playing Ona Lukozsaite. Sinclair appears at the beginning and end of the film "as a form of endorsement."
- The Wet Parade (1931) became a film directed by Victor Fleming in 1932. It starred Robert Young, Myrna Loy, Walter Huston, and Jimmy Durante.
- The Gnomobile (1937) was the basis of a 1967 Disney musical motion picture, The Gnome-Mobile.
- Oil! (1927) was the basis of There Will Be Blood (2007), starring Daniel Day-Lewis and Paul Dano. It was written, produced, and directed by Paul Thomas Anderson. The film received eight Oscar nominations and won two.
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