Uke may refer to:
- UKE, University Medical Center Hamburg-Eppendorf in Germany
- Ukulele, musical instrument
- Uke, a.k.a. Ukrainian, person identified with nationality of Ukraine
- Uke (martial arts), role in training
- Uke, role in relationship between males in yaoi or shōnen-ai media
- Ükä or Uke Tibetan, a term for the most widely-understood dialect of Tibetan