Ubiquitin B

Ubiquitin B

Identifiers Symbols UBB; RPS27A; UBA52; UBC External IDs OMIM: 191339 HomoloGene: 75104 GeneCards: UBB Gene

Gene Ontology
Molecular function • protein binding
Cellular component • nucleoplasm
• cytosol
• endosome membrane
• endocytic vesicle membrane
Biological process • cell cycle checkpoint
• G1 phase of mitotic cell cycle
• G1/S transition of mitotic cell cycle
• S phase of mitotic cell cycle
• M phase of mitotic cell cycle
• mitotic anaphase
• negative regulation of transcription from RNA polymerase II promoter
• activation of MAPK activity
• protein polyubiquitination
• mitotic cell cycle
• toll-like receptor signaling pathway
• antigen processing and presentation of peptide antigen via MHC class I
• antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
• MyD88-dependent toll-like receptor signaling pathway
• MyD88-independent toll-like receptor signaling pathway
• DNA repair
• transcription, DNA-dependent
• transcription initiation from RNA polymerase II promoter
• apoptotic process
• DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
• epidermal growth factor receptor signaling pathway
• transforming growth factor beta receptor signaling pathway
• Notch signaling pathway
• Notch receptor processing
• I-kappaB kinase/NF-kappaB cascade
• JNK cascade
• fibroblast growth factor receptor signaling pathway
• gene expression
• viral reproduction
• cellular membrane organization
• RNA metabolic process
• mRNA metabolic process
• endosomal transport
• virion assembly
• viral protein processing
• cytokine-mediated signaling pathway
• viral reproductive process
• negative regulation of transforming growth factor beta receptor signaling pathway
• anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
• negative regulation of type I interferon production
• positive regulation of type I interferon production
• cellular response to stress
• toll-like receptor 2 signaling pathway
• toll-like receptor 3 signaling pathway
• toll-like receptor 4 signaling pathway
• toll-like receptor 5 signaling pathway
• toll-like receptor 9 signaling pathway
• toll-like receptor 10 signaling pathway
• ion transmembrane transport
• TRIF-dependent toll-like receptor signaling pathway
• nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
• toll-like receptor TLR1:TLR2 signaling pathway
• toll-like receptor TLR6:TLR2 signaling pathway
• negative regulation of epidermal growth factor receptor signaling pathway
• antigen processing and presentation of exogenous peptide antigen via MHC class I
• regulation of apoptotic process
• negative regulation of apoptotic process
• positive regulation of I-kappaB kinase/NF-kappaB cascade
• innate immune response
• positive regulation of transcription from RNA polymerase II promoter
• egress of virus within host cell
• neurotrophin TRK receptor signaling pathway
• T cell receptor signaling pathway
• positive regulation of NF-kappaB transcription factor activity
• stress-activated MAPK cascade
• negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
• positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
• regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
• transmembrane transport
• regulation of transcription from RNA polymerase II promoter in response to hypoxia
• nucleotide-binding oligomerization domain containing signaling pathway
• cellular response to hypoxia
• apoptotic signaling pathway
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7314 n/a Ensembl ENSG00000170315 n/a UniProt P0CG47 n/a RefSeq (mRNA) NM_018955 n/a RefSeq (protein) NP_061828 n/a Location (UCSC) Chr 17:
16.28 – 16.29 Mb n/a PubMed search n/a

Ubiquitin is a protein that in humans is encoded by the UBB gene.

Read more about Ubiquitin B:  Function