Genetic Factors
Studies have shown that genetic factors play a role in the increased frequency of MS in the relatives of MS patients. However, identification of the genes that are involved has not been accomplished due to the small sample size. Generally, genes involved in the immune system are over-expressed and they implicate T-helper cell differentiation. T-helper cells are involved in the activation of T-cells which are responsible for entering the central nervous system and initiating demyelination processes.
Read more about this topic: Tumefactive Multiple Sclerosis
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