Clinical Signs and Symptoms
Initial symptoms of MS consist of both sensory and motor symptoms. According to Kidd, motor symptoms develop first followed by the sensory symptoms. The more common symptoms include spasticity, visual loss, difficulty in walking and paresthesia which is a feeling of tickling or numbness of the skin, commonly described as “pins and needles”. Symptoms of tumefactive MS often mimic a variety of other diseases including ischemic stroke, peroneal nerve palsy and intracranial neurologic disease. Subjects have been reported to suffer from a decreased motor control resulting in a ‘foot drop’, or significantly reduced leg movement. In other cases closer mimicking strokes, subjects may suffer from confusion, dizziness, and weakness in one side of the face. Symptoms also can mimic a neoplasm with symptoms such as headaches, aphasia, and/ or seizures.
Read more about this topic: Tumefactive Multiple Sclerosis
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