Trough may refer to:
- Trough (economics), the lowest turning point of a business cycle
- Trough (food) or manger, a container for animal feed
- Watering trough, a receptacle of drinking water for domestic and non-domestic livestock
- Trough (geology), a long depression less steep than a trench
- Trough (meteorology), an elongated region of low atmospheric pressure
- Trough (physics), the lowest point on a wave
- Trough level (medicine), the lowest level that a medicine is present in the body
- Langmuir-Blodgett trough, a laboratory instrument
- Battle of the Trough, a 1756 skirmish of the French and Indian War in West Virginia
- Sleightholme Beck Gorge - The Troughs, a Site of Special Scientific Interest in the Teesdale district of south-west County Durham, England
- The Trough, a gorge carved by the South Branch Potomac River in West Virginia
- Trough, an old word for an inkwell