Trehalose - Production

Production

Trehalose was previously being manufactured through an extraction process from cultured yeast, but, since production costs were prohibitive, use was limited to only certain cosmetics and chemicals.

In 1994, Hayashibara, a saccharified starch maker in Okayama prefecture, Japan, discovered a method of inexpensively mass-producing trehalose from starch. The following year, Hayashibara started manufacturing trehalose by activating two enzymes, the glucosyltrehalose-producing enzyme that changes the reducing terminal of starch into a trehalose structure, and the trehalose free enzyme that detaches this trehalose structure. As a result, a high-purity trehalose from starch can be mass produced for a very low price.

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