Treadwell is an English surname, and may refer to:
- Alexander Treadwell (b. 1946), New York politician
- Frederick Pearson Treadwell (1857-1919), American-Swiss chemist
- Liam Treadwell, English National Hunt jockey
- Sophie Treadwell (1885–1970), American playwright and journalist
- Timothy Treadwell (1957-2003), American environmentalist
- Valentine Treadwell (c. 1813–1888), New York politician
- William Dupré Treadwell (1885-1959), American-Swiss chemist
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