Transplant Rejection - Immunologic Mechanisms of Rejection

Immunologic Mechanisms of Rejection

Rejection is an adaptive immune response via cellular immunity (mediated by killer T cells inducing apoptosis of target cells) as well as humoral immunity (mediated by activated B cells secreting antibody molecules), though the action is joined by components of innate immune response (phagocytes and soluble immune proteins). Different types of transplanted tissues tend to favor different balances of rejection mechanisms.

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    Sarah Fielding (1710–1768)