Transferrin Saturation - Usual Values

Usual Values

Normal reference ranges are:

  • Serum iron: 60–170 μg/dl (10–30μmol/L)
  • TIBC: 240–450 μg/dl
  • Transferrin saturation: 15–50% (males), 12–45% (females)

μg/dl = micrograms per deciliter.

Laboratories often use different units and "normal" may vary by population and the lab techniques used. Look at the individual laboratory reference values to interpret a specific test (for instance, your own).

Pathology: hematology, hematologic diseases of RBCs and megakaryocytes / MEP (D50-69,74, 280-287)
Red
blood cells
↑
Poly-
cythemia
  • Polycythemia vera
↓
Anemia
Nutritional
  • Micro-: Iron deficiency anemia
    • Plummer-Vinson syndrome
  • Macro-: Megaloblastic anemia
    • Pernicious anemia
Hemolytic
(mostly Normo-)
Hereditary
  • enzymopathy: G6PD
  • glycolysis
    • PK
    • TI
    • HK
  • hemoglobinopathy: Thalassemia
    • alpha
    • beta
    • delta
  • Sickle-cell disease/trait
  • HPFH
  • membrane: Hereditary spherocytosis
    • Minkowski-Chauffard syndrome
  • Hereditary elliptocytosis
    • Southeast Asian ovalocytosis
  • Hereditary stomatocytosis
Acquired
  • Autoimmune
    • WAHA
    • CAD
    • PCH
  • membrane
    • PNH
  • MAHA
  • TM
    • HUS
  • Drug-induced autoimmune
  • Drug-induced nonautoimmune
  • Hemolytic disease of the newborn
Aplastic
(mostly Normo-)
  • Hereditary: Fanconi anemia
  • Diamond–Blackfan anemia
  • Acquired: PRCA
  • Sideroblastic anemia
  • Myelophthisic
Blood tests
  • MCV
    • Normocytic
    • Microcytic
    • Macrocytic
  • MCHC
    • Normochromic
    • Hypochromic
Other
  • Methemoglobinemia
  • Sulfhemoglobinemia
  • Reticulocytopenia
Coagulation/
coagulopathy
↑
Hyper-
coagulability
  • primary: Antithrombin III deficiency
  • Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden
  • Prothrombin G20210A
  • acquired:Thrombocytosis
    • essential
  • DIC
    • Congenital afibrinogenemia
    • Purpura fulminans
  • autoimmune
    • Antiphospholipid
↓
Hypo-
coagulability
Thrombocytopenia
  • Thrombocytopenic purpura: ITP
    • Evans syndrome
  • TM
    • TTP
  • Heparin-induced thrombocytopenia
  • May-Hegglin anomaly
Platelet function
  • adhesion
    • Bernard–Soulier syndrome
  • aggregation
    • Glanzmann's thrombasthenia
  • platelet storage pool deficiency
    • Hermansky–Pudlak syndrome
    • Gray platelet syndrome
Clotting factor
  • Hemophilia
    • A/VIII
    • B/IX
    • C/XI
  • von Willebrand disease
  • Hypoprothrombinemia/II
  • XIII
  • Dysfibrinogenemia

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns
Medical test: Serology, reference range: Clinical biochemistry blood tests (including BMP, CMP) (CPT 82000–84999)
Fluid/electrolytes
  • electrolytes
    • Na+/K+
    • Cl-/HCO3-
  • renal function, BUN-to-creatinine ratio
    • BUN/Creatinine
  • Ca
  • derived values: Plasma osmolality
  • Serum osmolal gap
Acid-base
  • Arterial blood gas
  • Base excess
  • Anion gap
  • CO2 content
Nutrition
  • Iron tests: Transferrin saturation = Serum iron / Total iron-binding capacity; Ferritin
  • Transferrin
  • Transferrin receptor
Endocrine
  • ACTH stimulation test
  • Thyroid function tests
    • TSH
  • Blood sugar: Glucose test
  • C-peptide
  • Fructosamine
  • Glycated hemoglobin
Metabolic
  • Blood lipids
Cardiovascular
  • Cardiac marker: Troponin test
  • CPK-MB test
  • LDH
  • Myoglobin
  • Glycogen phosphorylase isoenzyme BB
Digestive
  • Liver function tests: protein tests
    • Human serum albumin
    • Serum total protein
  • ALP
  • transaminases
    • ALT
    • AST
    • AST/ALT ratio
  • Bilirubin
    • Unconjugated
    • Conjugated
  • Amylase
  • Lipase
    • Pancreatic lipase

M: URI

anat/phys/devp/cell

noco/acba/cong/tumr, sysi/epon, urte

proc/itvp, drug (G4B), blte, urte

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

M: HRT

anat/phys/devp

noco/cong/tumr, sysi/epon, injr

proc, drug (C1A/1B/1C/1D), blte

M: DIG

anat (t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug (A2A/2B/3/4/5/6/7/14/16), blte


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