Towles may refer to:
- Places
- Towles, California, former name of Towle, California
- Towles Intermediate School, Fort Wayne, Indiana
- Towles Glacier
- People
- Dorothea Towles (1922–2006), model
- Gladys Towles Root (1905–1982), American attorney
- J. R. Towles (b. 1984), American baseball player
- Nat Towles (1905–1962), American musician, jazz and big band leader
- Tom Towles (b. 1950), American actor