Time-of-flight Mass Spectrometry - Hadamard Transform Time-of-flight Mass Spectrometry

Hadamard Transform Time-of-flight Mass Spectrometry

Hadamard transform TOF mass spectrometer is an instrument that can be used with a continuous ion source. Whereas traditional TOF MS analyzes one packet of ions at a time, waiting for the ions to reach the detector before introducing another ion packet, HT-TOFMS can analyze several ion packets simultaneously traveling in the flight tube. The ions packets are encoded by fast modulating the transmission of the ion beam in a manner based on a Hadamard matrix. The resulting spectra, however, can be deconvoluted based on knowledge of the encoding scheme.