Related Real Works
In 1821, Carl Friedrich Gauss wrote a ground-breaking treatise on the dynamics of an asteroid (1 Ceres). However, it was understood immediately and his method is still used today (see Gauss's method).
Two decades before Arthur Conan Doyle's writing, the American dynamic astronomer Simon Newcomb had published a series of books analyzing motions of planets in the solar system. The notoriously spiteful Newcomb could have been an inspiration for Professor Moriarty.
An example of mathematics that could not be criticized are the letters of Srinivasa Ramanujan, sent to several mathematicians at the University of Cambridge in 1913. Only one of them, G. H. Hardy, even recognized their merit. Despite being experts in the field, he and J.E. Littlewood added that many of them "defeated me completely; I had never seen anything in the least like them before."
Read more about this topic: The Dynamics Of An Asteroid
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—Ralph Waldo Emerson (1803–1882)