Tetracycline Response Element (TRE)
The tetracycline response element consists of 7 repeats of the 19bp bacterial tet-o sequence separated by spacer sequences. It is the tet-o that is recognized and bound by the TetR portion of Tet-On or Tet-Off. The TRE is usually placed upstream of a minimal promoter that has very low basal expression in the absence of bound Tet-Off (or Tet-On).
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Famous quotes containing the words response and/or element:
“It does me good to write a letter which is not a response to a demand, a gratuitous letter, so to speak, which has accumulated in me like the waters of a reservoir.”
—Henry Miller (1891–1980)
“All forms of beauty, like all possible phenomena, contain an element of the eternal and an element of the transitory—of the absolute and of the particular. Absolute and eternal beauty does not exist, or rather it is only an abstraction creamed from the general surface of different beauties. The particular element in each manifestation comes from the emotions: and just as we have our own particular emotions, so we have our own beauty.”
—Charles Baudelaire (1821–1867)