Tetracycline Response Element (TRE)
The tetracycline response element consists of 7 repeats of the 19bp bacterial tet-o sequence separated by spacer sequences. It is the tet-o that is recognized and bound by the TetR portion of Tet-On or Tet-Off. The TRE is usually placed upstream of a minimal promoter that has very low basal expression in the absence of bound Tet-Off (or Tet-On).
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Famous quotes containing the words response and/or element:
“It does me good to write a letter which is not a response to a demand, a gratuitous letter, so to speak, which has accumulated in me like the waters of a reservoir.”
—Henry Miller (1891–1980)
“Other sins only speak; murder shrieks out:
The element of water moistens the earth,
But blood flies upwards, and bedews the heavens.”
—John Webster (1580–1625)