Testicular Sperm Extraction

Testicular Sperm Extraction

Testicular sperm extraction (TESE) is the process of removing a small portion of tissue from the testicle under local anesthesia and extracting the few viable sperm cells present in that tissue for the purpose of intracytoplasmic sperm injection (ICSI). The testicular sperm extraction process is recommended to men who are unable to produce sperm by ejaculation as a result azoospermia, such as caused by primary testicular failure, congenital absence of the vas deferens or non-reconstructed vasectomy.

Intracytoplasmic sperm injection (ICSI) and testicular sperm extraction (TESE) have reduced the need for donor sperm.

Serum inhibin-B weakly indicates presence of sperm cells in the testes, raising chances for successfully achieving pregnancy through TESE, although the association is not very substantial, having a sensitivity of 0.65 (95% confidence interval : 0.56–0.74) and a specificity of 0.83 (CI: 0.64–0.93) for prediction the presence of sperm in the testes in non-obstructive azoospermia.

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