Adverse Effects and Overdose
Only mild and transient side effects have been observed, mostly immunological reactions like eosinophilia, itching and fever. Some patients develop human anti-mouse antibodies, so there is the theoretical possibility of anaphylactic reactions. High doses of IMMU-4 (up to 20-fold diagnostic arcitumomab dose) have not led to any serious events. One patient has been reported to develop a grand mal after application.
Radioactivity can lead to radiation poisoning. Since the dose of an arcitumomab application is about 10 mSv, such an overdose is unlikely.
Read more about this topic: Technetium (99m Tc) Arcitumomab
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