Syndrome of Inappropriate Antidiuretic Hormone Secretion - Causes

Causes

Some common causes of SIADH include:

  • Meningitis
  • Head injury
    • Subarachnoid hemorrhage
  • Cancers
    • Lung cancer (especially small-cell lung cancer, as well as other small-cell malignancies of other organs)
  • Infections
    • Brain abscess
    • Pneumonia
    • Lung abscess
  • Guillain Barre syndrome
  • Drugs
    • Chlorpropamide
    • Clofibrate
    • Phenothiazine
    • IfosfamideH
    • Cyclophosphamide
    • Carbamazepine
    • Selective serotonin reuptake inhibitors (SSRIs, a class of antidepressants)
    • Methylenedioxymethamphetamine (MDMA, commonly called Ecstasy. SIADH due to taking ecstasy was cited as a factor in the death of Leah Betts)
    • Oxytocin
    • Vincristine
    • Morphine
    • Amitriptyline
  • Hypothyroidism
  • sarcoidosis

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