Regions
The genome is functionally divided into 3 regions:
- Early: Expressed early in virus infection, i.e. BEFORE genome replication. Expression of early genes continues during the late stage of infection. Encodes non-structural proteins (i.e. not present in virus particle).
- Late: Expressed later in virus infection, i.e. DURING & AFTER genome replication. Encodes structural proteins (i.e. present in virus particle).
- Regulatory region: Contains transcriptional promoters & enhancers plus the unique origin of DNA replication.
Read more about this topic: SV40 Large T-antigen
Famous quotes containing the word regions:
“Nature seems to have taken a particular Care to disseminate her Blessings among the different Regions of the World, with an Eye to this mutual Intercourse and Traffick among Mankind, that the Natives of the several Parts of the Globe might have a kind of Dependance [sic] upon one another, and be united together by their common Interest.”
—Joseph Addison (1672–1719)
“We have wasted our spirit in the regions of the abstract and general just as the monks let it wither in the world of prayer and contemplation.”
—Alexander Herzen (1812–1870)
“In place of a world, there is a city, a point, in which the whole life of broad regions is collecting while the rest dries up. In place of a type-true people, born of and grown on the soil, there is a new sort of nomad, cohering unstably in fluid masses, the parasitical city dweller, traditionless, utterly matter-of-fact, religionless, clever, unfruitful, deeply contemptuous of the countryman and especially that highest form of countryman, the country gentleman.”
—Oswald Spengler (1880–1936)