Regions
The genome is functionally divided into 3 regions:
- Early: Expressed early in virus infection, i.e. BEFORE genome replication. Expression of early genes continues during the late stage of infection. Encodes non-structural proteins (i.e. not present in virus particle).
- Late: Expressed later in virus infection, i.e. DURING & AFTER genome replication. Encodes structural proteins (i.e. present in virus particle).
- Regulatory region: Contains transcriptional promoters & enhancers plus the unique origin of DNA replication.
Read more about this topic: SV40 Large T-antigen
Famous quotes containing the word regions:
“It is doubtful whether anyone who has travelled widely has found anywhere in the world regions more ugly than in the human face.”
—Friedrich Nietzsche (1844–1900)
“Within the regions of the air,
Compassed about with heavens fair,
Great tracts of land there may be found
Enriched with fields and fertile ground;
Where many numerous hosts
In those far distant coasts,
For other great and glorious ends,
Inhabit, my yet unknown friends.”
—Thomas Traherne (1636–1674)
“What is a television apparatus to man, who has only to shut his eyes to see the most inaccessible regions of the seen and the never seen, who has only to imagine in order to pierce through walls and cause all the planetary Baghdads of his dreams to rise from the dust.”
—Salvador Dali (1904–1989)